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The mucous membranes mouth, nose, ears, throat, genitals, and anus are most susceptible to infection with HSV. The cervix and urethra are also high target areas. Also susceptible are any areas that may be subject to abrasion, and warm, moist areas such as the upper thighs, underarms, hairline, lower back, perineum, scrotum, and buttocks — any areas when sweating is common. Herpes is most easily passed through inoculation from active lesions. The virus may also spread during times when there are no symptoms, and from sites that are seemingly inactive.
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